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Medical Biodegradable Polymers PLA AND PLGA
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Specifications |
PLA |
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1.¡¡Polylactide£¨PLA£©
1.1¡¡D,L- polylactide (D,L-PLA)
¡ñ D,L-PLA is a kind of amorphous polymer£¬whose glass transition temperature (Tg) is 50¡«60℃¡£
¡ñ Viscosity IV£º0.5¡«9 dl/g£¬molecular weight :5,000¡«700,000¡£
¡ñ It has been approved by American Food and Drug Administration(FDA) as carrier material of injectable microcapsules, microspheres and implants , and for internal fixation.
¡ñ It can be used as porous foam scaffold for cell culture in tissue engineering£¬which can be designed with different factor of porosity¡¢aperture and degradation velocity.
1.2 £Ì-polylactide£¨L-PLA£©
¡ñ L-PLA is a kind of crystalline polymer£¬whose Tg is 60¡«65℃¡£
¡ñ Fusing point: 175¡«185℃, viscosity IV£º0.5¡«9 dl/g£¬molecular weight : 5,000¡«700,000¡£
¡ñ Extensively applied in internal fixators such as bone plates, bone pins, surgical sutures, electro spun fibers, et al.
2. Poly(lactide-co-glycolide) (PLGA)
¡ñ DL-LA/GA£º90/10¡¢80/20¡¢75/25¡¢60/40¡¢50/50.
¡ñ DL-PLGA is a kind of amorphous polymer;Tg:45¡«55℃£¬viscosity IV£º0.10¡«2.0 dl/g£¬molecular weight 5,000¡«300,000.
¡ñ The polymers can be produced with variable structure property such as glass state and soft, fabricable materials¡£
¡ñ It can be used as medical films, and carrier material of sustained release dosage systems such as injectable microcapsules, injectable microspheres and implants .
¡ñ It can also be used as porous scaffold for cell culture in tissue engineering£¬which can be designed with different factor of porosity¡¢aperture and degradation velocity.
3.Thermosensitive polylactide hydrogels-MPEG-PLA¡¢MPEG-PLGA
¡ñ Amorphous polymers; Tg:45¡«55℃; viscosity IV£º0.10¡«1.0 dl/g; molecular weight :5,000¡«200,000.
¡ñ MPEG-PLA and MPEG-PLGA are more hydrophilic than PLA, and have all property of thermosensitive hydrogels.
¡ñ MPEG-PLA and MPEG-PLGA can completely dissolved in water at certain concentration at 4℃, but the aqueous solution rapidly turn to hydrogel at bod |
Company: |
Jinan Daigang Biomaterial Co., Ltd
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Contact: |
Mr. li daigang |
Address: |
jinan luoyuan |
Postcode: |
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Tel: |
86013075360818 |
Fax: |
86013075360818 |
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